RALPH L. SACCO, MD: The key is somebody who has now had a stroke, or a TIA, preventing an event — preventing a recurrence. Most of the time we talk about secondary or tertiary prevention. We're really talking about how to prevent a recurrent stroke. It's clear that if you've survived your stroke, you're at risk for a recurrence. If you have a recurrence, it's going to make a major impact. It will increase the chance of dying. It will clearly add more disability to your life. It's important for us to be thinking about ways to reduce the chance — in the survivors of stroke — the chance of a recurrent stroke.
PAUL J. MONIZ: You mentioned TIA. For those viewers who are just joining us, again could you explain what that is.
RALPH L. SACCO, MD: TIA is a warning sign, a transient ischemic attack — it's a brain attack. It may be a warning sign of a stroke. In TIA patients who are at high risk for stroke, we want to prevent a stroke and this fits into prevention as well.
PAUL J. MONIZ: Dr. Jamieson, as time goes on someone's chances of having another stroke actually increases. Can you give us the numbers? The breakdown?
DARA JAMIESON, MD: Certainly the risk accumulates over time. After you've had a TIA or after you've had one stroke, your risk of actually having another episode is highest right near that — in the next hours to days to weeks. But the risk continues to accumulate so that by one year, you may have a 5-10% chance of having another stroke. Or by five years, you may have a 30-35% chance of having another stroke. The process of prevention continues for many years, both in terms of lifestyle and in terms of medication.
PAUL J. MONIZ: So this is something that people have to be really serious about for the rest of their lives once it happens.